Membrane Biophysics and NMR

Publications




Peptides derived from the C-terminal domain of HIV-1 Viral Protein R in lipid bilayers: Structure, membrane positioning and gene delivery.

Marquette A, Leborgne C, Schartner V, Salnikov E, Bechinger B, Kichler A.

Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183149. doi: 10.1016/j.bbamem.2019.183149.

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Characterization of the DNA and Membrane Interactions of a Bioreducible Cell-Penetrating Foldamer in its Monomeric and Dimeric Form.

Aisenbrey C, Douat C, Kichler A, Guichard G, Bechinger B.

J Phys Chem B. 2020 Jun 4;124(22):4476-4486. doi: 10.1021/acs.jpcb.0c01853.

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Structure, interactions and membrane topology of HIV gp41 ectodomain sequences.

Aisenbrey C, Bechinger B.

Biochim Biophys Acta Biomembr. 2020 Jul 1;1862(7):183274. doi: 10.1016/j.bbamem.2020.183274.

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Membrane pore-formation correlates with the hydrophilic angle of histidine-rich amphipathic peptides with multiple biological activities.

Lointier M, Aisenbrey C, Marquette A, Tan JH, Kichler A, Bechinger B.

Biochim Biophys Acta Biomembr. 2020 Aug 1;1862(8):183212. doi: 10.1016/j.bbamem.2020.183212.

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Highly synergistic antimicrobial activity of magainin 2 and PGLa peptides is rooted in the formation of supramolecular complexes with lipids.

Aisenbrey C, Amaro M, Pospisil P, Hof M, Bechinger B.

Sci Rep. 2020 Jul 15;10(1):11652. doi: 10.1038/s41598-020-68416-1.

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Copper-binding motifs Xxx-His or Xxx-Zzz-His (ATCUN) linked to an antimicrobial peptide: Cu-binding, antimicrobial activity and ROS production.

Bouragubaa, B., Glattard, E., Naudé, M. ÅLa, Pelletier, R., Aisenbrey, C., Bechinger, B., Lebrun, V. Faller, P.

J. Inorg. Biochem. 2020 231, 111255. doi: 10.1016/j.jinorgbio.2020.111255.

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The reversible non-covalent aggregation into fibers of PGLa and magainin 2 preserves their antimicrobial activity and synergism.

juhl, D.W., Glattard, E., Lointier, M., Babilis, B., Bechinger, B.

Front. Cell. Infect. Microbiol. 2020 10, 526459. doi: 10.3389/fcimb.2020.526459.

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Revealing the mechanisms of synergistic action of magainin antimicrobial peptides.

Bechinger, B., Juhl, D.W., Glattard, E., and Aisenbrey, C.

Front.Med. Technol. 2020 2, 615494. doi.org/10.3389/fmedt.2020.615494.

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Structure, membrane topology and cholesterol interactions of the membrane proximal region - transmembrane helical anchor sequence of gp41 from HIV.

Aisenbrey, C., Rifi, O., and Bechinger, B.

Sci. Rep. 2020 10, 22278. doi : 10.1038/s41598-020-79327-6

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Two distinct amphipathic peptide antibiotics with systemic efficacy.

Lakshmaiah Narayana, J., Mishra, B., Lushnikova, T., Wu, Q., Chhonker, Y. S., Zhang, Y., Zarena, D., Salnikov, E.S., Dang, X., Makarov, E., Wang, F., Murphy, C., Foster, K. W., Fey, P. D., Bechinger, B., Gorantla, S., Murry, D. J., and Wang, G.

PNAS 2020 117(32):19446-19454 doi: 10.1073/pnas.2005540117.

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Structure, topology and dynamics of membrane-associated peptides by solid-state NMR.

Bechinger, B. and Salnikov, E.S.

Book: Solid-state NMR: Applications in Biomembrane Structure. Chapter 7, pp. 322-365 Biophysical Society 2020 doi: 10.1007/978-1-62703-275-9_16


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